The physiologic importance of electrolytes in body fluid

1.      Na⁺ is the major determinant of plasma osmolality.

2.      K⁺ is the major determinant of intercellular osmolality.

3.      The plasma HCO₃ reflects acute changes in acid base balance.

        4.    Serum ionized Ca⁺⁺ is responsible for many important physiological processes.