Immunodeficiency disorders are a group of disorders in which
part of the immune system is missing or defective. Therefore, the body's
ability to fight infections is impaired. As a result, the person with an
immunodeficiency disorder will have frequent infections that are generally more
severe and last longer than usual.
Acquired immunodeficiency disorders
Acquired immunodeficiency is more common than congenital
immunodeficiency. It is the result of an infectious process or other disease.
For example, the human immunodeficiency virus (HIV) is the virus that causes
acquired immunodeficiency syndrome (AIDS). However, this is not the most common
cause of acquired immunodeficiency.
Acquired immunodeficiency often occurs as a complication of
other conditions and diseases. For example, the most common causes of acquired
immunodeficiency are malnutrition, some types of cancer, and infections. People
who weigh less than 70% of the average weight of persons of the same age and
gender are considered to be malnourished. Examples of types of infections that
can lead to immunodeficiency are chickenpox, cytomegalovirus, German measles,
measles, tuberculosis, infectious mononucleosis (Epstein-Barr virus), chronic
hepatitis, lupus, and bacterial and fungal infections.
Sometimes, acquired immunodeficiency is brought
on by drugs used to treat another condition. For example, patients who have an
organ transplant are given drugs to suppress the immune system so the body will
not reject the organ. Also, some chemotherapy drugs, which are given to treat
cancer, have the side effect of killing cells of the immune system. During the
period of time that these drugs are being taken, the risk of infection
increases. It usually returns to normal after the person stops taking the
drugs.
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