Showing posts with label Cancer. Show all posts
Showing posts with label Cancer. Show all posts

Tuesday, February 11, 2014

How do cancer cells evade immune system?

Cancer cells can evade immune system by following mechanisms?
  1. Failure to produce tumor antigen.
  2. Mutations in MHC genes or genes needed for antigen processing.
  3. Production of immune-suppressive proteins.

What is immunosurveillance?

Cancer immunosurveillance is a theory where proposed that lymphocytes acts as sentinels in recognizing and eliminating continuously arising nascent transformed cells. Cancer immunosurveillance appears to be an important host protection process that inhibits carcinogenesis and maintains regular cellular homeostasis. It has also been suggested that immunosurveillance primarily functions as a component of a more general process of cancer immunoediting.