Friday, November 2, 2018

What vascular changes occur in acute inflammation?

Vascular changes in acute inflammation are as follows:
  1. Vasodilation is induced by the action of several mediators, mainly histamine, on vascular smooth muscle.
  2. Vasodilation is quickly followed by increased permeability of the microvasculature.
  3. Engorgement of small vessels with slowly moving red cells, a condition termed stasis,
    which is seen as vascular congestion and localized redness of the involved tissue.
  4. As stasis develops, blood leukocytes, principally neutrophils, accumulate along the vascular endothelium.

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