If repair cannot be accomplished by regeneration alone, it occurs by replacement of the injured cells with connective tissue, leading to the formation of a scar, or by a combination of regeneration of some residual cells and scar formation.
Steps involved in repair in scar formation:
- Clot formation
- Inflammation
- Angiogenesis and formation of granulation tissue,
- Migration and proliferation of fibroblasts,
- Collagen synthesis,
- Connective tissue remodeling.
