Metaplasia is a double-edged sword because in respiratory tract respiratory epithelium is changed into squamous epithelium to protect against noxious stimulant but lost its ability mucus secretion and cilliary action which is important for protection against infection.
Moreover, the influences that predispose to metaplasia, if persistent, can initiate malignant transformation in metaplastic epithelium.
Moreover, the influences that predispose to metaplasia, if persistent, can initiate malignant transformation in metaplastic epithelium.
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